کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4035439 1263526 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simulation analysis of bandpass filtering properties of a rod photoreceptor network
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Simulation analysis of bandpass filtering properties of a rod photoreceptor network
چکیده انگلیسی

The bandpass filtering properties of a rod network were studied via computer simulations. Sinusoidal current stimuli were applied to a single rod model to characterize its temporal filtering properties. The simulated frequency response revealed that a single rod behaves as a bandpass filter whose characteristics are affected by the stimulus strength and frequency. We analyzed the contribution of individual ionic currents to bandpass filtering and found that the filtering of small signals is largely regulated by the calcium-dependent currents IK(Ca) and ICl(Ca), whereas the filtering of large signals is regulated by the hyperpolarization-activated current, Ih. Furthermore, rod network modeling by electrically interconnecting the single rod models revealed that the acceleration of signals that spread laterally through the rod network is attributed to IK(Ca) and not Ih.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vision Research - Volume 49, Issue 9, 11 May 2009, Pages 970–978
نویسندگان
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