Recyclable, highly efficient and low cost nano-MgO for amide synthesis under SFRC: A convenient and greener ‘NOSE’ approach

A clean synthesis of amide derivatives has successfully been accomplished utilizing reusable nano-MgO under ‘SFRC’ (solvent free reaction condition). The ‘green-ness’ of this protocol makes it a benign alternative for the large scale synthesis.

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► A clean synthesis of amide derivatives has successfully been accomplished.
► Nano-MgO was found to be highly active.
► Reusable nano-MgO under ‘SFRC’ has been used in a ‘NOSE’ approach.
► Measurement of “green-ness” by using green metrics.
► The ‘green-ness’ of this protocol makes it a benign alternative method.