Reliability and minimal detectable change of gait kinematics in people who are hypermobile

• Reliability of gait analysis was quantified for hypermobile and normal flexibility participants.
• There was no significant difference between hypermobile and normal flexibility variability.
• MDCs are likely to exceed the differences between hypermobile and normal gait.

ObjectiveTo evaluate intra- and inter-session reliability of gait data in hypermobile and normal adults, and from this, determine the minimum detectable change (MDC) through 3D gait analysis (GA) measurement.MethodsThirteen people with normal flexibility (Beighton score 0.82 ± 1.2) and 14 hypermobile people (Beighton score 5.6 ± 1.6) completed three separate GA sessions. Lower limb joint kinematics were recorded in three planes of motion. Intra- and inter-session variability was calculated and compared using single factor ANOVA. MDC at 95% confidence level was calculated for the hypermobile cohort.ResultsThere was no significant difference between hypermobile and normal flexibility adults in intra- or inter-session variability for any parameters measured. For both groups, mean intra-session variability was under 2.0° for all joints in all three planes. Inter-session variability was greater; sagittal plane joint angles were most reliable, showing less than 3.0° variability for all joints. Frontal plane variability was below 3.5°. Highest variability was seen in internal/external rotation angles, with hip, knee and ankle showing 4.6°, 5.1° and 3.2° variability respectively. These reliability values are reflected in MDC results, with pelvis and sagittal plane joint angles showing the lowest MDCs.ConclusionsIn hypermobile people, 3DGA kinematic parameters are repeatable. Hypermobile people's joint laxity does not affect variability of their kinematic gait analysis measures. The results will help guide future clinical trial design; future work should ensure that differences expected to be observed are measurable, and exceed the MDC for a given parameter.