کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
408717 679041 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modelling self-sustained rhythmic activity in lamprey hemisegmental networks
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر هوش مصنوعی
پیش نمایش صفحه اول مقاله
Modelling self-sustained rhythmic activity in lamprey hemisegmental networks
چکیده انگلیسی

Recent studies of the lamprey spinal cord have shown that hemisegmental preparations can display rhythmic activity in response to a constant input drive. This activity is believed to be generated by a network of recurrently connected excitatory interneurons. A recent study found and characterized self-sustaining rhythmic activity—locomotor bouts—after brief electrical stimulation of hemisegmental preparations. The mechanisms behind the bouts are still unclear. We have developed a computational model of the hemisegmental network. The model addresses the possible involvement of NMDA, AMPA, acetylcholine, and metabotropic glutamate receptors as well as axonal delays in locomotor bouts.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurocomputing - Volume 69, Issues 10–12, June 2006, Pages 1097–1102
نویسندگان
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