کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
408718 | 679041 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Role of frequency-dependent weighing of inputs on frequency regulation of a pacemaker-driven rhythm
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
هوش مصنوعی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
We examined the frequency-dependent efficiency of positive and negative inputs onto pacemaker neurons of the pyloric rhythm. When neuromodulation to the pyloric circuit was blocked, pyloric neurons became quiescent. In the pacemaker neurons, we injected series of sinusoidal currents of different frequencies. At slow frequencies, voltage peak amplitudes were significantly larger than troughs. This trend reversed at higher frequencies. A computational model suggests that rapid A- and slower T-type currents can produce this excitability profile, and that a frequency dependence preference of negative and positive inputs impinging onto pacemaker neurons can play an important role in homeostatic stabilization of the rhythm.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurocomputing - Volume 69, Issues 10–12, June 2006, Pages 1103–1107
Journal: Neurocomputing - Volume 69, Issues 10–12, June 2006, Pages 1103–1107
نویسندگان
Inbar Saraf-Sinik, Yair Manor,