A two-dimensional population density approach to modeling the dLGN/PGN network

The interaction of two populations of integrate-and-fire-or-burst neurons representing thalamocortical cells from the dorsal lateral geniculate nucleus (dLGN) and thalamic reticular cells from the perigeniculate nucleus (PGN) is studied here using a population density approach. A two-dimensional probability density function that evolves according to a time-dependent advection-reaction equation gives the distribution of cells in each population over the membrane potential (v)(v) and de-inactivation level (h)(h) of the low-threshold Ca2+Ca2+ current ITIT. The response of the dLGN/PGN network is studied for optic tract stimulation protocols of different amplitude, duty cycle, and frequency.