کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4112217 1606002 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Temporary forced oral breathing affects neonates oxygen consumption, carbon dioxide elimination, diaphragm muscles structure and physiological parameters
ترجمه فارسی عنوان
تنفس دهان و دندان موقت تأثیر مصرف اکسیژن نوزادان، حذف دی اکسید کربن، ساختار عضلات دیافراگم و پارامترهای فیزیولوژیک
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
چکیده انگلیسی

ObjectivesWe studied adaptation of diaphragm, oxygen consumption and carbon dioxide elimination to forced oral breathing (lasting for only 4 days) following reversible bilateral nasal obstruction performed on day 8 post-natal male rats.MethodsDiaphragm myosin heavy chain (MHC) composition, oxygen consumption, carbon dioxide elimination and hormones level were analysed during nasal obstruction period.ResultsDiaphragm muscle showed significant increases in adult isoforms (MHC 1, 2a) in oral breathing group versus control. Reversible nasal obstruction was associated with a decrease of oxygen consumption and carbon dioxide elimination. Nasal obstruction period was associated with reduced growth of the olfactory bulbs and an initial decrease in lung growth. One day after implementing nasal obstruction, basal corticosterone levels had increased (by over 1000). Oral breathing was also associated with a lower level of thyroid hormone.ConclusionsWe conclude that a 4 day nasal obstruction period in young rats leads to hormonal changes and to Diaphragm myosin heavy chain structural adaptation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 78, Issue 11, November 2014, Pages 1807–1812
نویسندگان
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