کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4115102 1606105 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lymphatic malformations of the head and neck: Introduction of a disease score for children, Cologne Disease Score (CDS)
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
Lymphatic malformations of the head and neck: Introduction of a disease score for children, Cologne Disease Score (CDS)
چکیده انگلیسی

SummaryObjectiveA clinical staging system for children with lymphatic malformations that would allow for a standardized comparison of disease and treatment outcomes.MethodsWe developed an examination sheet for the determination of a disease score ranging from 0 (worst) points to 10 (best) points, Cologne Disease Score (CDS). Disfigurement, dysphagia, dysphonia, dyspnea and an observer statement towards progression were contributing to CDS. Each parameter yielded two, one or zero points. Two points were given when no limitation was seen in the patient concerning the respective item. One point was given at mild limitation and zero points were given when considerable limitation in the respective item could be observed. We evaluated 26 patients with lymphatic malformations of the head and neck retrospectively by completing one examination sheet for each patient-visit.ResultsFour patients had an initial CDS value of three or less points (severe disease-group). After therapy the mean value of their score increased only slightly to 3.9 ± 2.6 points. Six patients had an initial CDS value of four, five or six points (advanced disease-group). After treatment their mean score value increased dramatically to 9.0 ± 1.5 points (P < 0.001). Sixteen patients initially had seven points or higher (moderate disease-group), they had 9.8 ± 0.4 points after treatment.ConclusionsThe evaluation of the CDS was easy and expeditious. The score itself was a good predictor in view of the outcome. This new disease score for paediatric patients might be appropriate to evaluate therapeutic trials in paediatric patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 70, Issue 7, July 2006, Pages 1205–1212
نویسندگان
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