کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4115818 1606103 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The safety of preoperative sedation in children with sleep-disordered breathing
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
The safety of preoperative sedation in children with sleep-disordered breathing
چکیده انگلیسی

SummaryObjectiveTo prospectively monitor children who received preoperative sedation with midazolam hydrochloride prior to adenotonsillectomy (T&A) for treatment of sleep-disordered breathing with continuous pulse-oximetry to detect potential respiratory compromise.DesignProspective, observational study.SettingHospital-based pediatric otolaryngology practice.PatientsSeventy children, aged 1–12 years, diagnosed with sleep-disordered breathing by clinical evaluation or polysomnography (PSG), with a median RDI of 14.25, undergoing T&A.MethodsChildren underwent a standardized anesthesia protocol including preoperative oral midazolam hydrochloride 0.5 mg/kg, standard American Society of Anesthesiologists (ASA) monitoring, mask induction with sevoflurane, muscle relaxant with reversal if indicated, and intravenous dexamethasone sodium phosphate 0.5 mg/kg. Children were monitored in the hospital until discharge criteria were met. Selected children with severe OSA were monitored overnight on the pediatric floor or the pediatric intensive care unit. Adverse respiratory events were defined as upper airway obstruction, hypoventilation, desaturation, bradycardia, or sustained lethargy.Main outcome measuresIncidence of pre and postoperative obstructive complications.ResultsDuring the study period only two patients (2.9%) had a measurable adverse event directly related to the administration of the sedation.ConclusionBased on sporadic reports of adverse airway events in children with obstructive sleep apnea receiving sedation, these children frequently do not receive preoperative sedation. Given the low morbidity of preoperative sedation in our population, many children with sleep-disordered breathing may safely be pre-medicated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 70, Issue 9, September 2006, Pages 1517–1521
نویسندگان
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