کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4130085 1606505 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cytokeratin-, calponin-, and p63-positive chondroblastoma with extensive soft tissue involvement and vascular invasion: a potential diagnostic dilemma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی آسیب‌شناسی و فناوری پزشکی
پیش نمایش صفحه اول مقاله
Cytokeratin-, calponin-, and p63-positive chondroblastoma with extensive soft tissue involvement and vascular invasion: a potential diagnostic dilemma
چکیده انگلیسی

Chondroblastomas are rare bone tumors, accounting for less than 2% of all bone tumors. Although generally benign, there are instances of aggressive tumor behavior with extensive soft tissue invasion and even metastasis. In this report, we detail an instance where the tumor displayed extensive soft tissue invasion. As there is tumor heterogeneity in terms of morphologic appearance as well as a varied immunohistochemistry profile, a diagnosis of chondroblastoma may not be straightforward if the initial biopsy sample did not include the more characteristic area. In our case, the tumor expressed cytokeratin, calponin, and p63 in addition to S-100, potentially raising a diagnosis of a mixed tumor. The differential diagnosis and biologic behavior of chondroblastomas are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Diagnostic Pathology - Volume 15, Issue 1, February 2011, Pages 58–63
نویسندگان
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