Myxoid dermatofibrosarcoma protruberans of the scrotum: A rare diagnosis in an unreported location

Dermatofibrosarcoma Protuberans (DFSP) represents a low grade, locally aggressive mesenchymal neoplasm with characteristic clinicopathologic, immunohistochemical, and molecular findings. Myxoid DFSP is an uncommon variant, with only few cases reported in the literature and may present a diagnostic challenge on histopathologic examination. We report the first case of myxoid DFSP arising in the scrotum of a 38 year-old man and describe the morphologic and immunohistochemical findings. Recognition of this variant at unusual sites is clinically important because the differential diagnosis includes benign and malignant tumors which could lead to under or over-treatment.