کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4139060 1272193 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Overweight and Obesity in a Sample of Children With Autism Spectrum Disorder
ترجمه فارسی عنوان
اضافه وزن و چاقی در نمونه ای از کودکان مبتلا به اختلال طیف اوتیسم
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی

ObjectiveTo determine the prevalence of overweight/obese status in children with autism spectrum disorders (ASD), identify associated characteristics, and develop a model to predict weight status.MethodsThe prevalence of overweight and obesity was determined in 2769 children with ASD enrolled in the Autism Speaks Autism Treatment Network, a collaboration of 17 academic centers, and compared with a national sample matched for age, sex, and race. Associations in the ASD sample between weight status and demographic and clinical variables, such as age, race, head circumference, and adaptive functioning, were tested using ordinal logistic regression. The accuracy of a final model that predicted weight status based on early life variables was evaluated in a validation sample.ResultsThe prevalence of overweight and obesity were 33.9% and 18.2%, respectively; ASD was associated with a higher risk of obesity (but not overweight) relative to the national sample (odds ratio [OR], 1.16; 95% confidence interval [CI], 1.05–1.28; P = .003). In the adjusted analysis, overweight/obese status was significantly associated with Hispanic ethnicity (OR, 1.99; 95% CI, 1.37–2.89), parental high school education (OR, 1.56; 95% CI, 1.09–2.21), high birth weight (OR, 1.56; 95% CI, 1.11–2.18), macrocephaly (OR, 4.01; 95% CI, 2.96–5.43), and increased somatic symptoms (OR, 1.41; 95% CI, 1.01–1.95). A prediction model designed to have high sensitivity predicted low risk of overweight/obesity accurately, but had low positive predictive value.ConclusionsThe prevalence of obesity in children with ASD was greater than a national sample. Independent associations with increased weight status included known risk factors and macrocephaly and increased level of somatic symptoms. A model based on early life variables accurately predicted low risk of overweight/obesity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Academic Pediatrics - Volume 15, Issue 4, July–August 2015, Pages 396–404
نویسندگان
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