کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4155049 1273735 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vanishing fetal lung malformations: Prenatal sonographic characteristics and postnatal outcomes
ترجمه فارسی عنوان
ناپایداری ناهنجاریهای ریه جنینی: خصوصیات سونوگرافی قبل از تولد و نتایج پس از تولد
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی

Background/purposeThe purpose of this study was to examine the natural history and outcomes of prenatally diagnosed lung masses that appear to undergo complete regression before birth.MethodsAn IRB-approved retrospective review was performed on 100 consecutive fetuses with a congenital lung malformation at a single fetal center. Prenatal and postnatal imaging as well as outcomes of vanishing fetal masses was analyzed and compared to those with persistent fetal masses.ResultsSeventeen lesions (17%) became sonographically undetectable at 35.3 ± 2.3 weeks gestation. Vanishing fetal masses were associated with microcystic disease (100% vs. 69%, p = 0.005) and a low initial congenital pulmonary airway malformation volume ratio (CVR; 0.31 ± 0.35 vs. 0.70 ± 0.66, p = 0.002) when compared to those with persistent fetal lesions. Based on postnatal CT imaging and pathology data, 10.3% of all fetal masses completely regressed. The positive predictive value and negative predictive value of prenatal ultrasound for detecting lung malformations in late gestation were 96% and 43%, respectively. All infants with vanishing fetal lesions were asymptomatic at birth and were more likely to be managed nonoperatively (75% vs. 22%, p < 0.0001) when compared to infants with persistent fetal masses.ConclusionsVanishing lung lesions late in gestation are relatively common and are associated with a low CVR and microcystic disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Surgery - Volume 50, Issue 6, June 2015, Pages 978–982
نویسندگان
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