کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4155444 1273746 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Factors affecting short-term neurodevelopmental outcome in children operated on for major congenital anomalies
ترجمه فارسی عنوان
عوامل موثر بر نتیجه کوتاه مدت رشد عصبی در کودکان مبتلا به ناهنجاری های مادرزادی عمده
کلمات کلیدی
نتیجه ناباروری، ناتوانی مادرزادی غیر قلبی، عوامل خطر
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی

PurposeIdentify clinical and socio-demographic risk-factors affecting short-term neurodevelopmental outcome (NDO) in children operated on for abdominal and thoracic congenital anomalies (CA).MethodsProspective cohort observational study on newborns operated on for non-cardiac major CA. Evaluations were conducted at 6 and 12 months of age. Univariate linear regression and multivariate regression were conducted to analyze the impact on NDO of clinical and sociodemographic variables. Infants were evaluated with the Bayley Scales of Infant and Toddler Development—3rd Edition.ResultsOne-hundred-fifty-five children were enrolled. They were affected by the following anomalies: Esophageal Atresia (N = 41), Congenital Diaphragmatic Hernia (N = 42), Midgut Malformations (N = 34), Abdominal Wall Defects (N = 18), Colorectal Malformations (N = 20). There were no statistically significant differences among the five groups of CA as to NDO. Variables which reached statistical significance at multivariate regression (p ≤ 0.001) at 6 and 12 months as to cognitive and motor development were: ventilatory time, associated malformations, medical appliances for feeding, number of surgery and length of hospital stay.ConclusionsOn the average, children born with CA show a NDO within normal range. The identified risk-factors could prompt health care professionals to conduct a close surveillance on most vulnerable children giving them the best chance to reach their full potential.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Surgery - Volume 50, Issue 7, July 2015, Pages 1125–1129
نویسندگان
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