کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4155581 | 1273751 | 2014 | 4 صفحه PDF | دانلود رایگان |
Background/purposeThe purpose of this study was to retrospectively investigate whether laparoscopy-aided gastrostomy placement (LGP) improved or worsened gastroesophageal reflux (GER) in neurological impairment (NI) patients.MethodsSubjects included 26 NI patients nourished via nasogastric tubes (age, 1–17 years; median, 6 years). They were divided into groups based on the percentage of time with an esophageal pH < 4.0 (reflux index: RI) before LGP: Group 1 (GI, n = 13), RI < 5.0%; Group II (GH, n = 13), RI ≥ 5.0%. Acid/nonacid reflux episodes (RE) were evaluated using combined pH-multichannel intraluminal impedance (pH-MII) monitoring, and gastric emptying was measured with the C breath test before and after LGP.ResultsRI and number of RE evaluated with pH analyses and number of total/acid distal and proximal bolus RE with pH-MH increased significantly in GI. RI and acid clearance time with pH analyses and number of total bolus RE with pH-MII decreased significantly in GH. Gastric emptying parameters did not change significantly in GI, whereas the half-gastric emptying time and gastric emptying coefficient improved significantly in GH.ConclusionLGP reduces GER in NI patients with pathological GER by improving gastric emptying, although it has a paradoxical influence on those without pathological GER.
Journal: Journal of Pediatric Surgery - Volume 49, Issue 12, December 2014, Pages 1742–1745