Pyloric atresia: Comorbidity determines outcome

Pyloric atresia is a congenital form of gastric outlet obstruction. The obstruction is relieved surgically, but survival is determined by the presence of additional anomalies. Herein, we report two cases of pyloric atresia. Our first patient was a neonate with epidermolysis bullosa who died of sepsis. The second was an infant who presented with postprandial emesis and had an uncomplicated postoperative course. We discuss the current understanding and management of this rare malformation.