Does the Use of Pacifier Affect Gastro-Esophageal Reflux in Preterm Infants?

This crossover study showed that non-nutritive sucking, provided with a pacifier in 30 preterm infants, had no effect on acid and nonacid gastro-esophageal reflux evaluated by esophageal pH-impedance, and thus may be reasonably used in preterm neonates with symptoms of gastro-esophageal reflux.Trial registrationClinicalTrials.gov: NCT02023216.