کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4164938 1607450 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quantity and Timing of Maternal Prenatal Smoking on Neonatal Body Composition: The Healthy Start Study
ترجمه فارسی عنوان
مقدار و زمانبندی سیگار کشیدن مادران قبل از تولد در ترکیب بدن نوزاد: مطالعه شروع سالم
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی

ObjectiveTo examine the dose-dependent and time-specific relationships of prenatal smoking with neonatal body mass, fat mass (FM), fat-free mass (FFM), and FM-to-FFM ratio, as measured by air-displacement plethysmography (PEA POD system).Study designWe analyzed 916 mother–neonate pairs participating in the longitudinal prebirth cohort Healthy Start study. Maternal prenatal smoking information was collected in early, middle, and late pregnancy by self-report. Neonatal body composition was measured with the PEA POD system after delivery. Multiple general linear regression models were adjusted for maternal and neonatal characteristics.ResultsEach additional pack of cigarettes smoked during pregnancy was associated with significant decreases in neonatal body mass (adjusted mean difference, −2.8 g; 95% CI, −3.9 to −1.8 g; P < .001), FM (−0.7 g; 95% CI, −1.1 to −0.3 g; P < .001), and FFM (−2.1 g; 95% CI, −2.9 to −1.3 g; P < .001). Neonates exposed to prenatal smoking throughout pregnancy had significantly lower body mass (P < .001), FM (P < .001), and FFM (P < .001) compared with those not exposed to smoking. However, neonates of mothers who smoked only before late pregnancy had no significant differences in body mass (P = .47), FM (P = .43), or FFM (P = .59) compared with unexposed offspring.ConclusionExposure to prenatal smoking leads to systematic growth restriction. Smoking cessation before late pregnancy may reduce the consequences of exposure to prenatal smoking on body composition. Follow-up of this cohort is needed to determine the influence of catch-up growth on early-life body composition and the risk of childhood obesity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 165, Issue 4, October 2014, Pages 707–712
نویسندگان
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