کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4166408 1607498 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ischemia-Reperfusion and Neonatal Intestinal Injury
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Ischemia-Reperfusion and Neonatal Intestinal Injury
چکیده انگلیسی

We review research relating ischemia/reperfusion to injury in the neonatal intestine. Epidemiologic evidence suggests that the most common form of necrotizing enterocolitis is not triggered by a primary hypoxic-ischemic event. Its late occurrence, lack of preceding ischemic events, and evidence for microbial and inflammatory processes preclude a major role for primary hypoxic ischemia as the sentinel pathogenic event. However, term infants, especially those with congenital heart disease who have development of intestinal necrosis, and those preterm infants with spontaneous intestinal perforations, are more likely to have intestinal ischemia as a primary component of their disease pathogenesis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 158, Issue 2, Supplement, February 2011, Pages e25–e28
نویسندگان
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