کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4167588 1607541 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age
چکیده انگلیسی

ObjectivesOur aim was to determine the extent to which infant growth—in weight-for-length—from birth to 6 months is associated with systolic blood pressure (SBP) at 3 years and to determine whether this association varies with birth size.Study designIn 530 children from the prospective cohort Project Viva, we measured birth length and 6-month weight and length with research standard instruments and SBP at age 3 years with a Dinamap automated recorder. We derived weight-for-length z-scores (WFL-z) and analyzed data with mixed effects regression models.ResultsThe mean (SD) WFL-z was 0.47 (0.75) at birth and 0.70 (0.96) at 6 months. Mean (SD) SBP at 3 years was 91.7 (9.4) mm Hg. After adjusting for confounding variables and birth WFL-z, child SBP was 1.0 mm Hg (95% CI 0.2, 1.8) higher for each z-score increment in 6-month WFL-z. The SBP of children in the lowest birth WFL-z quartile and the highest 6-month WFL-z quartile was 5.5 mm Hg (95% CI 2.6, 8.4) higher than that of children in the highest birth and lowest 6-month WFL-z quartiles.ConclusionsMore rapid increase in weight-for-length, a measure of adiposity, in the first 6 months of life is associated with higher early childhood SBP, particularly in children who are thin at birth.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 151, Issue 6, December 2007, Pages 670–674
نویسندگان
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