Plasma Plant Sterol Levels Do Not Reflect Cholesterol Absorption in Children with Smith-Lemli-Opitz Syndrome

Although the ratios of plant sterols to cholesterol in plasma has been used as a surrogate for cholesterol absorption in adults and children, these ratios may not accurately reflect cholesterol absorption in children with SLOS. These ratios should not be used as a surrogate for cholesterol absorption in children without further validation.