کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4169090 1607554 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope
چکیده انگلیسی

ObjectiveTo determine whether midodrine hydrochloride therapy can prevent vasovagal syncope (VVS) in pediatric patients.Study designChildren with recurrent syncope (n = 26) were randomly assigned into 2 groups. Group I comprised children given midodrine hydrochloride as first-line therapy in addition to conventional therapy, and group II comprised patients receiving conventional therapy only. Repeat head-up tilt (HUT) testing and follow-up of least 6 months were conducted to evaluate the therapeutic effectiveness and side effects of midodrine in treating VVS in children.ResultsThe HUT-based effective rate was significantly higher in group I than in group II (75% vs 20%; P < .05). During the follow-up period, the recurrence of syncope was significantly lower in group I than in group II (P < .05).ConclusionsMidodrine hydrochlorate is effective in treating VVS in children, especially in preventing recurrent episodes. Few side effects were observed in the present study.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Pediatrics - Volume 149, Issue 6, December 2006, Pages 777–780
نویسندگان
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