کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4169159 | 1607557 | 2006 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Venous thrombosis and thromboembolism in children with osteomyelitis Venous thrombosis and thromboembolism in children with osteomyelitis](/preview/png/4169159.png)
ObjectiveTo determine the prevalence and clinical features of deep vein thrombosis (DVT) complicating osteomyelitis during childhood.Study designWe retrospectively reviewed medical records of all patients with osteomyelitis admitted to Children’s Medical Center Dallas between July 1, 2003 and December 31, 2004. Analysis was performed on patients with proximal upper or lower extremity, pelvic or vertebral osteomyelitis (a subgroup considered to be at highest risk for infection-related thrombosis).ResultsThirty-five patients had confirmed osteomyelitis of the proximal humerus, proximal tibia/fibula, femur, pelvis, or vertebrae. Ten of these 35 children (29%) developed DVT during the acute infection based on imaging studies performed. Eight thrombi occurred adjacent to the infection and two occurred in relation to central venous catheters. Six of the 10 children with DVT also had evidence of infection disseminated to lung, brain, or heart, compared with only 1 of 25 patients without DVT (P = .001). Hospitalization was longer in those with DVT than without (33.5 v. 14.2 days, P = .001).ConclusionThromboembolic complications can occur in the setting of osteomyelitis, and affected patients may be at higher risk of disseminated infection.
Journal: The Journal of Pediatrics - Volume 149, Issue 4, October 2006, Pages 537–541