کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4169611 | 1607563 | 2006 | 5 صفحه PDF | دانلود رایگان |

ObjectivesTo test the hypothesis that the level of relative humidity (RH) in which preterm infants are nursed might influence their postnatal skin maturation.Study designIn 22 preterm infants (GA 23-27 weeks), transepidermal water loss (TEWL) was determined at postnatal ages (PNA) of 0, 3, 7, 14, and 28 days. At a PNA of 7 days, the infants were randomized to care at either 50% or 75% RH.ResultsTEWL decreased at a slower rate in infants nursed at the higher RH. At a PNA of 28 days, TEWL was about twice as high in infants nursed at 75% RH (22 ± 2 g/m2 h) than in those nursed at 50% RH (13 ± 1 g/m2 h; P < .001).ConclusionsThe results indicate that the level of RH influences skin barrier development, with more rapid barrier formation in infants nursed at a lower RH. The findings have an impact on strategies for promoting skin barrier integrity in extremely preterm infants.
Journal: The Journal of Pediatrics - Volume 148, Issue 5, May 2006, Pages 613–617