کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4174959 1276162 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effectiveness of Vitamin A in the Prevention of Complications of Prematurity
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Effectiveness of Vitamin A in the Prevention of Complications of Prematurity
چکیده انگلیسی

BackgroundTo assess the effectiveness of vitamin A supplementation in very low birth weight (VLBW) infants to prevent complications of prematurity.MethodsThis was a retrospective cohort study to determine the effectiveness of vitamin A in preventing complications of prematurity in VLBW infants. Vitamin A was delivered intramuscularly at a dose of 5000 IU, three times weekly during the first 28 days of life.ResultsOf the 187 eligible VLBW infants, we excluded from the analysis (due to death or transfer to another hospital), 16 infants weighing <1000 g and 17 weighing 1000–1500 g. Sixty VLBW infants received the vitamin supplement. We observed no differences between the groups in the duration of oxygen therapy or in the risk of bronchopulmonary dysplasia. The risk of sepsis was up to three times higher among the infants who were given the vitamin A supplement.ConclusionGiven the increased risk of sepsis in patients weighing >1000 g, the risk associated with repeated intramuscular injections of vitamin A and the modest clinical results described, we do not believe the universal administration of vitamin A to VLBW infants to be justified as prophylaxis for bronchopulmonary dysplasia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pediatrics & Neonatology - Volume 55, Issue 5, October 2014, Pages 358–362
نویسندگان
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