کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4195429 1608928 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Patient factors may predict anastomotic complications after rectal cancer surgery: Anastomotic complications in rectal cancer
ترجمه فارسی عنوان
عوامل بیمار ممکن است عوارض آناستوموتیک را پس از جراحی سرطان رکتوم پیش بینی کنند: عوارض آناستوموز در سرطان رکتوم
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
چکیده انگلیسی


• Risk factors for anastomotic complications include malnutrition, radiation, and ischemia.
• Transfusions have been associated with increased complications.
• Hemoglobin level <11 gr/dl might be associated with increased risk of anastomotic leak.
• Presence of diverting stoma does not affect the incidence of anastomotic leaks.

PurposeAnastomotic complications following rectal cancer surgery occur with varying frequency. Preoperative radiation, BMI, and low anastomoses have been implicated as predictors in previous studies, but their definitive role is still under review. The objective of our study was to identify patient and operative factors that may be predictive of anastomotic complications.MethodsA retrospective review was performed on patients who had sphincter-preservation surgery performed for rectal cancer at a tertiary medical center between 2005 and 2011.Results123 patients were included in this study, mean age was 59 (26–86), 58% were male. There were 33 complications in 32 patients (27%). Stenosis was the most frequent complication (24 of 33). 11 patients required mechanical dilatation, and 4 had operative revision of the anastomosis. Leak or pelvic abscess were present in 9 patients (7.3%); 4 were explored, 2 were drained and 3 were managed conservatively. 4 patients had permanent colostomy created due to anastomotic complications. Laparoscopy approach, BMI, age, smoking and tumor distance from anal verge were not significantly associated with anastomotic complications. After a multivariate analysis chemoradiation was significantly associated with overall anastomotic complications (Wall = 0.35, p = 0.05), and hemoglobin levels were associated with anastomotic leak (Wald = 4.09, p = 0.04).ConclusionOur study identifies preoperative anemia as possible risk factor for anastomotic leak and neoadjuvant chemoradiation may lead to increased risk of complications overall. Further prospective studies will help to elucidate these findings as well as identify amenable factors that may decrease risk of anastomotic complications after rectal cancer surgery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Medicine and Surgery - Volume 4, Issue 1, March 2015, Pages 11–16
نویسندگان
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