Study on the Mechanism of Compound Mistletoe Fluidextract in Relieving Hypertension

ObjectiveTo observe the effect of Fufang Jisheng Liujin Gao (Compound Mistletoe Fluidextract) on blood pressure in the spontaneous hypertensive rats (SHR) and the renal hypertensive dogs (RHD).MethodsThe blood pressure-decreasing effects of single administration and 14-day consecutive administration of Compound Mistletoe Fluidextract (CMF) in SHR and RHD were investigated and compared with that of Niuhuang Jiangya Wan (Bezoar Hypertension-relieving Pills).ResultsBoth single administration and 14-day consecutive administration of CMF had significant hypotensive effects in SHR and RHD.ConclusionThe hypotensive action of CMF is gradual, but lasts for a longer period, with a dose-effect relationship in a range of doses.