Effects of the Aidi Dripping Pills on Immune Functions of the Tumor-bearing Mouse

ObjectiveTo study the effects of Aidi Dripping Pills on immune functions of the tumor-bearing mouse on the basis of the previous experimental studies on its tumor-inhibiting and life-prolonging effects.MethodsBy using the transplantation tumor mouse models, the effects of Aidi Dripping Pills on the lymphocyte transformation rate and the hemolysin formation in the S180 tumor-bearing mice, and on the phagocytic function of macrophages in the abdominal cavity of H22 tumor-bearing mice were investigated.ResultsIn the 2.25 g/kg and 1.125 g/kg Aidi Dripping Pills groups, the lymphocyte transformation rates in the S180 tumor-bearing mice were significantly higher than that of the control group (P<0.01). In all the Aidi Dripping Pills groups, HC50 significantly increased (P<0.01 or P<0.05), carbon granular clearance significantly raised, and both the phagocytic index and phagocytic coefficient were significantly higher than those in the control group (P<0.01 or P<0.05).ConclusionThe Aidi Dripping Pills can significantly increase the cellular immune function, the humoral immune function and the phagocytic function of the mononuclear-macrophages, so it may show anti-tumor effects by enhancing the function of the reticuloendothelial system.