کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4208760 1280460 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Disposable versus reusable jet nebulizers for cystic fibrosis treatment with tobramycin
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Disposable versus reusable jet nebulizers for cystic fibrosis treatment with tobramycin
چکیده انگلیسی

BackgroundJet nebulizers are commonly used to administer aerosolized tobramycin to CF patients. The aim of this study was to assess the performance of disposable jet nebulizers as an alternative to reusable nebulizers such as the Pari LC Plus.MethodFrom a survey conducted in 49 CF centers in France, 18 disposable jet nebulizer systems were selected. An in vitro study was performed with 20 jet nebulizer/air source combinations (18 disposable and 2 reusable) to determine their performance with tobramycin solution (300 mg/5 mL). A scintigraphic deposition study in baboons was performed to validate the in vitro data.ResultsIn vitro and in vivo results correlated. There was no overall relationship between the compressed air source and nebulizer performance, but the nebulizer interface was responsible for significantly different results.ConclusionsNone of the disposable nebulizers tested in this study can be recommended as an alternative to the Pari LC Plus nebulizer for tobramycin.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cystic Fibrosis - Volume 10, Issue 2, March 2011, Pages 86–92
نویسندگان
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