کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4210389 1280585 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cystic lung disease is not uncommon in men with tuberous sclerosis complex
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Cystic lung disease is not uncommon in men with tuberous sclerosis complex
چکیده انگلیسی

SummaryObjectiveTo assess the frequency of cystic lung disease suggestive of pulmonary lymphangiomyomatosis in men with tuberous sclerosis complex.Patients and methodsRetrospective review of CT scans of the chest and abdomen on 29 men with tuberous sclerosis complex encountered during a 13-year period, 1998 to 2010.ResultsCystic lung disease (defined as ≥4 cysts) was seen in 11 of 29 men (38%) with tuberous sclerosis complex. The mean age of those with cystic lung disease was 46.3 ± 19.1 years. None of the patients had experienced pneumothorax or chylothorax and none had undergone a lung biopsy for evaluation of cystic lung disease. Lymphangiomyomatosis had been diagnosed in two of 11 patients with cystic lung disease. Renal angiomyolipomas were demonstrated in 14 of 25 patients (56%) with renal imaging available; all 14 had multiple bilateral renal involvement. In this limited cohort of patients, the presence of cystic lung disease did not correlate with age, smoking exposure or the presence of renal AMLs.ConclusionWe conclude that tuberous sclerosis complex -related lymphangiomyomatosis may not be rare in men but is milder in severity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 106, Issue 11, November 2012, Pages 1586–1590
نویسندگان
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