کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4211431 1280640 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Exhaled nitric oxide measurements: Correction equation to compare hand-held device to stationary analyzer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Exhaled nitric oxide measurements: Correction equation to compare hand-held device to stationary analyzer
چکیده انگلیسی

SummaryIntroductionExhaled nitric oxide (FENO) is a reliable non-invasive marker of airway inflammation. In 2003 FENO chemiluminescence analyzer (NIOX®; Aerocrine AB, Solna, Sweden) was approved by U.S. Food and Drug Administration for monitoring asthma therapy. Recently, the same company developed a portable device using electrochemical sensors (NIOX-MINO®; Aerocrine AB). The aim of our study was to compare NIOX-MINO® FENO values to those obtained by NIOX® and to calculate a correction equation.MethodsTwo adequate measurements obtained by NIOX® and NIOX-MINO® were recorded in 32 subjects (16 females, mean age 41 years).ResultsFENO values measured by NIOX-MINO® were systematically higher than those obtained by NIOX® (47.1 ppb, IC 95% 35.2–59.1 and 36.9 ppb, IC 95% 25.0–49.0, respectively). There was a significant correlation (r = 0.998, p < 0.001) between FENO measured by the two analyzers and the following conversion equation was calculated as:FENO(NIOX®) = −1.656(SE = 0.61) + 0.808(SE = 0.009) × FENO(NIOX-MINO®)DiscussionFENO values measured by the portable nitric oxide analyzer are reliable and strongly correlated with values obtained by the standard stationary device, with a systematic difference observed between the two instruments' values that can be described by the conversion equation we provided. This equation will help clinicians and researchers to compare data obtainable by the two analyzers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 102, Issue 9, September 2008, Pages 1272–1275
نویسندگان
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