کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4212074 1280662 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Right ventricular dilation on CT pulmonary angiogram independently predicts mortality in pulmonary embolism
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Right ventricular dilation on CT pulmonary angiogram independently predicts mortality in pulmonary embolism
چکیده انگلیسی

SummaryBackgroundThe aim of this study was to determine the prognostic significance of right ventricular dilation on CT pulmonary angiogram in acute pulmonary embolism and to distinguish if this feature predicts mortality independently of the Pulmonary Embolism Severity Index, an established admission severity score.MethodsA retrospective study of patients admitted with pulmonary embolism confirmed by CT pulmonary angiogram to three teaching hospitals in East Scotland between January 2005 and July 2007. Two radiologists judged presence of right ventricular dilation on CT pulmonary angiogram independently. The outcome of interest was 30 day mortality. Multivariable logistic regression was used to compare this outcome in patients with right ventricular dilation compared to those without right ventricular dilation, adjusting for Pulmonary Embolism Severity Index score.ResultsThere were 585 patients included and 30.4% had right ventricular dilation on CT pulmonary angiogram. Patients with right ventricular dilation had increased 30 day mortality rates compared to patients without right ventricular dilation (12.4% vs. 5.4%; p = 0.006). Survival analysis showed that a significantly greater proportion of deaths in the right ventricular dilation group occurred within the first 48 h after admission compared to the group without right ventricular dilation (45.5% deaths vs. 9.1%; p = 0.016). On multivariable analysis, adjusting for Pulmonary Embolism Severity Index score, right ventricular dilation was independently associated with increased 30 day mortality (OR 2.98; 95% CI 1.54–5.75; p = 0.001).ConclusionRight ventricular dilation on CT pulmonary angiogram is an independent predictor of 30 day mortality in acute pulmonary embolism.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 104, Issue 7, July 2010, Pages 1057–1062
نویسندگان
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