کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4212273 | 1280673 | 2006 | 5 صفحه PDF | دانلود رایگان |
SummaryBackgroundAssociations have been reported between irritable bowel syndrome (IBS) and asthma.AimsTo explore the inter-relations between these conditions in a general population sample.SubjectsA randomly selected community sample of 5492 adults.MethodsAll of the subjects were invited for a medical interview. Those subjects suspected to have either asthma and/or IBS underwent spirometry with post-bronchodilator test if indicated. The labeling of subjects as having IBS was based on Rome II criteria.Results4762 subjects agreed to take part (86.7% response). Prevalence rates for IBS, and currently active asthma were 7.1% and 3.8%, respectively. Logistic regression showed independent associations between IBS and most asthma symptom categories. There was no significant independent association between IBS and chronic bronchitis. The odds ratio with 95% confidence interval (CI) for IBS and current asthma was 1.79 (1.06–3.03).ConclusionsThese observations indicate the necessity of further community-based studies to elucidate the possible common pathogenic mechanisms involved in two disease entities.
Journal: Respiratory Medicine - Volume 100, Issue 1, January 2006, Pages 110–114