Are transition zone biopsies necessary in transrectal ultrasound-guided transperineal prostate biopsy protocol? Results of a Chinese population-based study

PurposeThe purpose of this study was to determine the utility of routine transperineal transition zone (TZ) biopsies.Materials and MethodsA total of 1028 consecutive patients underwent transrectal ultrasound-guided prostate biopsies for the first time. Sextant biopsies and additional two-core TZ biopsies were performed.ResultsProstate cancer detection rate was increased by sampling two additional cores from TZ.ConclusionsTransition zone biopsies might be reserved to improve the detection rate of prostate cancer in transperineal biopsy protocol.