Catalytic oxidation of tetralin by biologically active copper and palladium complexes

The biologically active complexes [Cu(CTZ)4]Cl2 (1), [Cu(CTZ)2Cl2]2 (2) and Pd(CTZ)2Cl2 (3) were evaluated as catalyst precursors for the homogeneous oxidation of tetralin under aerobic conditions. The catalytic reaction was carried out using the following conditions determined for [Cu(CTZ)4]Cl2: T = 373 K, Pair = 35.0 atm, substrate/catalyst ratio = 700, reaction time = 9 h. These complexes were effective catalyst precursors for the selective oxidation of tetralin to α-tetralone and α-tetralol. Copper complexes 1 and 2 performed better than the palladium complex both in conversion (over 50%) and selectivity towards the production of α-tetralone (one/ol = 3).

The biologically active complexes [Cu(CTZ)4]Cl2, [Cu(CTZ)2Cl2]2 and Pd(CTZ)2Cl2 were evaluated as catalyst precursors for the homogeneous oxidation of tetralin under aerobic conditions. Copper complexes were found to perform better than the palladium complexes under the studied conditions, leading to higher conversions and selectivity towards α-tetralone.Figure optionsDownload as PowerPoint slide