کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4314092 | 1290023 | 2010 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Postnatal exposure to synthetic predator odor (TMT) induces quantitative modification in fear-related behaviors during adulthood without change in corticosterone levels Postnatal exposure to synthetic predator odor (TMT) induces quantitative modification in fear-related behaviors during adulthood without change in corticosterone levels](/preview/png/4314092.png)
Environmental stimuli and adverse experiences in early life may result in behavioral and physiological changes in adulthood. In several animal species, the odors cues are crucial in the setting of adaptive behaviors, especially towards predators. However, little is known about the effects of postnatal exposure to predator odor on the later physiological and behavioral responses to this natural stressor. Thus, the aim of this study was to investigate the effects of a postnatal exposure to synthetic predator odor (TMT) in mice pups on later adult fear-related behaviors and corticosterone levels in response to this specific stimulus. Pups postnatally exposed to only water showed later in adult life behavioral responses when exposed to TMT that were statistically different from mice that were exposed as neonates to TMT. In addition, mice exposed as neonates to TMT showed a decrease of fear-related behaviors while no differences occurred in the corticosterone levels between both groups.
Research highlightsLittle is known about the effects of postnatal exposure to predator odor on the later physiological and behavioral reponses to this natural stressor in mice. The results of the present study indicated that pups postnatally exposed to only water showed later in adult life behavioral responses when exposed to TMT different from mice that were exposed as neonates to TMT while no differences occurred in the corticosterone lecvels between both groups.
Journal: Behavioural Brain Research - Volume 215, Issue 1, 20 December 2010, Pages 58–62