کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4314262 1290031 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of amygdaloid glutamatergic receptors on sensory and emotional pain-related behavior in the neuropathic rat
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Influence of amygdaloid glutamatergic receptors on sensory and emotional pain-related behavior in the neuropathic rat
چکیده انگلیسی
The role of amygdaloid glutamatergic receptors (GluRs) in maintenance of the sensory versus emotional component of neuropathic pain was studied by assessing monofilament-induced limb withdrawal response (sensory pain) and aversive place-conditioning behavior (emotional pain) following amygdaloid administration of various glutamatergic compounds in nerve-injured animals. The results indicate that endogenous activation of amygdaloid group I metabotropic GluRs, mGluR1 and mGluR5, and the NMDA-R contributes to maintenance of sensory and emotional components of neuropathic pain. The predominant effect by amygdaloid group I mGluRs was facilitation of emotional-like pain behavior.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 209, Issue 1, 1 May 2010, Pages 174-178
نویسندگان
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