کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4319041 1613276 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Long-lasting and transgenerational effects of an environmental enrichment on memory formation
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Long-lasting and transgenerational effects of an environmental enrichment on memory formation
چکیده انگلیسی

It has long been believed that genetically determined, but not environmentally acquired, phenotypes can be inherited. However, a large number of recent studies have reported that phenotypes acquired from an animal's environment can be transmitted to the next generation. Moreover, epidemiology studies have hinted that a similar phenomenon occurs in humans. This type of inheritance does not involve gene mutations that change DNA sequence. Instead, it is thought that epigenetic changes in chromatin, such as DNA methylation and histone modification, occur. In this review, we will focus on one exciting new example of this phenomenon, transfer across generations of enhanced synaptic plasticity and memory formation induced by exposure to an “enriched” environment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Bulletin - Volume 85, Issues 1–2, 25 April 2011, Pages 30–35
نویسندگان
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