کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4322507 | 1291713 | 2007 | 10 صفحه PDF | دانلود رایگان |
SummaryPrimary visual cortex recombines inputs from magnocellular (M) and parvocellular (P) streams to create functionally specialized outputs. Understanding these input-output relationships is complicated by the fact that layer 4B, which provides outputs to dorsal visual areas, contains multiple cell types. Using a modified rabies virus that expresses green fluorescent protein, we show that layer 4B neurons projecting to MT are a majority spiny stellate, whereas those projecting to V2 are overwhelmingly pyramidal. Regardless of cell type, MT-projecting neurons have larger cell bodies, more dendritic length, and are deeper within layer 4B. Furthermore, MT-projecting pyramidal neurons are located preferentially underneath cytochrome oxidase blobs, indicating that MT-projecting neurons of both types restrict their dendrites to M-recipient zones. We conclude that MT-projecting layer 4B neurons are specialized for the fast transmission of information from the M pathway, while V2-projecting neurons are likely to mediate slower computations involving mixed M and P signals.
Journal: - Volume 55, Issue 5, 6 September 2007, Pages 799–808