کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4323561 1613800 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Corticospinal excitability is reduced in a simple reaction time task requiring complex timing
ترجمه فارسی عنوان
تحریک پذیری کورتیکسپسن در یک کار زمان واکنش ساده نیاز به زمان بندی پیچیده دارد
کلمات کلیدی
فعال سازی عصبی، پیچیدگی پاسخ، تحریک مغناطیسی ترانس مغناطیسی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی


• TMS was used to probe motor excitability during simple and complex RT tasks.
• Prior to response output motor excitability was lower for the complex task.
• Initiation-related activation may increase at a reduced rate for complex tasks.

Increasing the complexity of a movement has been shown to result in longer simple reaction time (RT), which has been attributed to sequencing or timing requirements following the go-signal. However, RT differences may also be due to differences in corticospinal excitability (CE) as previous studies have found an enhanced excitatory state of corticospinal neurons in complex tasks. Transcranial magnetic stimulation (TMS) was used in the present study to probe the excitability of the motor pathway during the simple RT interval for single (simple) versus multiple (complex) key press responses. Premotor RT data indicated that participants responded significantly (p<.001) faster in the simple task compared to the complex task, confirming response complexity was manipulated appropriately. Analysis of the CE data indicated that motor evoked potential (MEP) amplitudes increased with time following the go-signal in both conditions and that MEP amplitudes in the simple task were significantly larger than those in the complex task when evoked within 75 ms of movement onset (p=.009). These findings suggest that the rate of increase for initiation-related neural activation is reduced for complex as compared to simple movements, which may partially explain differences in RT.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1642, 1 July 2016, Pages 319–326
نویسندگان
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