Suppression of electrical synapses between retinal amacrine cells of goldfish by intracellular cyclic-AMP

► I measured regulation of gap junctions and electrical synapses of fish amacrine cells. ► To our knowledge of gap junctions, this is the first report by dual patch clamps. ► This study served to clarify regulation by intracellular cAMP on electrical synapses. ► I showed best assessment about block of gap junctions by high cAMP but not cGMP. ► Novel mechanisms, apart from protein kinases, will be present in teleost retina.