کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4325621 1614020 2011 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Right hemispheric participation in semantic decision improves performance
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Right hemispheric participation in semantic decision improves performance
چکیده انگلیسی

Functional neuroimaging studies in healthy adults demonstrate involvement of a left-lateralized network of frontal, temporal, and parietal regions during a variety of semantic processing tasks. While these areas are believed to be fundamental to semantic processing, it is unclear if task performance is correlated with differential recruitment of these or other brain regions. The objective of this study was to identify the structures underlying improved accuracy on a semantic decision task. We also investigated whether extra-scanner performance on the Boston Naming Test (BNT) and Semantic Fluency Test (SFT), neuropsychological measures of semantic retrieval, is correlated with specific areas of activation during the semantic decision/tone decision (SDTD) fMRI task. Fifty-two healthy, right-handed individuals performed a block-design SDTD task. Regression analyses revealed that increased performance on this task was associated with activation in the right inferior parietal lobule. Higher SFT performance resulted in greater recruitment of right frontal regions; improved performance on BNT was associated with more widespread activation in prefrontal, temporal, and parietal cortex bilaterally, although this activation appeared to be stronger in the right hemisphere. Overall, our results suggest that improved performance on both intra- and extra-scanner measures of semantic processing are associated with increased recruitment of right hemispheric regions.


► We examined the cortical substrates of semantic processing.
► Semantic decision accuracy is associated with activation in right parietal cortex.
► The right hemisphere is important to improved semantic decision performance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1419, 24 October 2011, Pages 105–116
نویسندگان
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