Electroencephalographic characterization of seizure activity in the synapsin I/II double knockout mouse

► Seizure behavior in SynDKO mice follows a strict pattern. ► EEG during seizures in SynDKO mice shows generalized sharp wave/spiking activity. ► The EEG shows a variable degree of uniformity during different seizure behaviors. ► EEG during truncus dominated seizure activity shows more variability. ► EEG during isolated myoclonic activity shows less variability.