کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4330594 | 1614267 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ultrasonic evoked responses in rat cochlear nucleus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
Numerous studies have reported auditory brainstem responses evoked by stimuli within the “normal” hearing range of rats, with maximum sensitivity peaking around 16Â kHz. Yet rats also emit and respond to sounds in the ultrasonic (US) frequency range (30-100Â kHz). However, very few electrophysiological studies have recorded auditory brainstem responses using US stimuli, and none have exceeded 70Â kHz. We report here short-latency (1-3Â ms) evoked potentials recorded in rat cochlear nucleus (CN) to US stimuli ranging from 40 to 90Â kHz. Robust responses were recorded in 33 of 36 CN recording sites to stimuli ranging from 40 to 60Â kHz; and twenty-eight of these sites continued to yield well-defined responses out to 90Â kHz. Latencies systematically increased and overall amplitudes decreased with increasing US frequency. Amplitudes differed significantly in the three CN subnuclei, being largest in posterior-ventral (PVCN) and smallest in anterior-ventral (AVCN). The fact that well-defined responses can be recorded to stimuli as high as 90Â kHz significantly extends the recorded upper frequency range of neural activity in the brainstem auditory pathway of the rat. These evoked potential results agree with the well-documented behavioral repertoire of rats in the US frequency range.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1172, 3 October 2007, Pages 40-47
Journal: Brain Research - Volume 1172, 3 October 2007, Pages 40-47
نویسندگان
Yi Du, Junli Ping, Nanxin Li, Xihong Wu, Liang Li, Gary Galbraith,