The sensory neuron and the triumph of Camillo Golgi

While Golgi's concept of the sensory neuron provided sound reasons for his rejection of the polarity principles underlying the ‘neuron doctrine’, it is now apparent that his concern about recovery of function after injury and the vast modern findings of ephemerality of connexin-clustered connections in the cerebral cortex and elsewhere in the central nervous system, and credibly termed ‘reticularist’, has somewhat eclipsed the polarized neuron doctrine of reflex physiology with the “fixed and immutable” connections championed by Cajal. Although Golgi's view was not the result of incisive reasoning based on subsequently confirmed observation, both principles espoused by these combatant Nobel laureate partners have proven robustly operative in different spheres and time frames of neural activity that have vastly enhanced contemporary understanding of neural connectivity.