کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4335922 1295189 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Visualization of spiral ganglion neurites within the scala tympani with a cochlear implant in situ
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Visualization of spiral ganglion neurites within the scala tympani with a cochlear implant in situ
چکیده انگلیسی
Current cochlear histology methods do not allow in situ processing of cochlear implants. The metal components of the implant preclude standard embedding and mid-modiolar sectioning, and whole mounts do not have the spatial resolution needed to view the implant within the scala tympani. One focus of recent auditory research is the regeneration of structures within the cochlea, particularly the ganglion cells and their processes, and there are multiple potential benefits to cochlear implant users from this work. To facilitate experimental investigations of auditory nerve regeneration performed in conjunction with cochlear implantation, it is critical to visualize the cochlear tissue and the implant together to determine if the nerve has made contact with the implant. This paper presents a novel histological technique that enables simultaneous visualization of the in situ cochlear implant and neurofilament-labeled nerve processes within the scala tympani, and the spatial relationship between them.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroscience Methods - Volume 179, Issue 2, 15 May 2009, Pages 201-207
نویسندگان
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