کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4336833 | 1295230 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Magnetic resonance microscopy of spinal cord injury in mouse using a miniaturized implantable RF coil
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
A magnetic resonance neuroimaging method is described for high-resolution imaging of spinal cord injury in live mouse. The method is based on a specially designed radio frequency coil system formed by a combination of an implantable coil and an external volume coil. The implantable coil is a 5 mm Ã 10 mm rectangular design with a 9.1 pF capacitor and 22 gauge copper wire and optimal for surgical implantation over the cervical or thoracic spine. The external volume coil is a standard birdcage resonator. The coils are inductively overcoupled for imaging the spinal cord at 9.4 T magnetic field strength. The inductive overcoupling provides flexibility in tuning the resonant frequency and matching the impedance of the implanted coil remotely using the tuning and matching capabilities of the volume coil. After describing the implementation of the imaging setup, in vivo data are gathered to demonstrate the imaging performance of the coil system and the feasibility of performing MR microscopy on injured mouse spinal cord.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroscience Methods - Volume 159, Issue 1, 15 January 2007, Pages 93-97
Journal: Journal of Neuroscience Methods - Volume 159, Issue 1, 15 January 2007, Pages 93-97
نویسندگان
Mehmet Bilgen,