کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4337928 1614832 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A functional MRI study of deception among offenders with antisocial personality disorders
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
A functional MRI study of deception among offenders with antisocial personality disorders
چکیده انگلیسی


• The deception of ASPD subjects can be differentiated by brain BOLD activities.
• The greater BOLD activities under deception were correlated with the capacity to lie.
• DPLC, ACC and IPL were associated with deception among people with ASPD.

Deceit is a core feature of antisocial personality disorder (ASPD), and the study of deception in ASPD has important implications for identifying the underlying mechanism of ASPD. A great deal of functional neuroimaging literature has described the neural correlates of deception in healthy volunteers, but there have been few imaging studies examining people with ASPD. The neural correlates of lie-telling in ASPD, and which specific brain activities are related to the capacity to lie, are unclear. In this study, 32 offenders who satisfied the Personality Diagnostic Questionaire-4 and PDI-IV (Personality Disorder Interview) criteria for ASPD were divided into three groups based on their capacity for deception, which was evaluated based on the deceitfulness criterion of the PDI-IV ASPD. All offenders underwent functional magnetic resonance imaging (fMRI) while responding to questions in a truthful, inverse, or deceitful manner. We primarily created contrasts in the brain activities between truth-telling and lie-telling, and then computed the Pearson’s correlation coefficients between activities contrasts of individual, i.e. BOLD (blood-oxygen-level-dependent) strength during deception minus that during truth-telling, and the capacity for deception. Our results indicated that the bilateral dorsolateral prefrontal cortex extending to the middle frontal gyrus, the left inferior parietal lobule, and the bilateral anterior cingulate gyrus/medial superior frontal gyrus were associated with deception among people with ASPD. As the capacity for deception increased, the contrasted brain activities of the above regions decreased. This study found that truthful and untruthful communications of ASPD subjects can be differentiated in terms of brain BOLD activities, and more importantly, this study is the first to use fMRI to discover that BOLD activities during deception are correlated with the capacity to lie. The latter finding might challenge the diagnostic accuracy of lie detection and may also caution that greater attention should be given to detecting untruths in individuals who are skilled at lying.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 244, 6 August 2013, Pages 90–98
نویسندگان
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