Changes in corticomotor excitability and inhibition after exercise are influenced by hand dominance and motor demand

▶Cortico-motor excitability and cortical inhibition were measured after hand tasks. ▶We compared motor demand (rate of movement) and hand (dominant vs. nondominant). ▶Excitability was reduced and cortical inhibition increased after all tasks. ▶The most demanding task had the least post-exercise effect, and vice-versa. ▶The effect of exercise on excitability and inhibition is inverse to motor demand.