Coordination of NMDA-induced rhythmic activity in the trigeminal and hypoglossal nerves of neonatal mice in vitro

► We examined neuronal mechanisms of jaw/tongue coordination during fictive suckling. ► Low-frequency rhythmic trigeminal activity was synchronized to hypoglossal activity. ► Low-frequency trigeminal activity disappeared after a rostral midline transection. ► Low-frequency hypoglossal activity remained after a rostral midline transection. ► Transected midline region may underlie the jaw/tongue coordination during suckling.